IS Clinical’s most popular product, this fast-acting, long-term, results-oriented formula decreases the appearance of fine lines and wrinkles, visibly evens skin tone, and is excellent for blemish-prone skin. Touted by physicians as "remarkable" and "phenomenal," Active Serum usually produces results within a couple of days. Apply 3-4 drops to the palm and dab and smooth evenly over face using fingertips. Potent activity will be noted upon application, as evidenced by a cooling tingling sensation. Excellent for all skin types and all ages, this powerful botanical serum leaves the skin moist and smooth.